Step 1. Gathering Alternate Drug Names/Terms

It’s easiest to compose a keyword search in Word.

  • Open a Word document.

English Generic Names

  • Type the English generic name for asciminib (title of the Martindale’s  monograph) into your Word document or copy the monograph title and paste it into the Word document.
  • If you included a salt name/s (e.g. mepesuccinate, sodium, hydrochloride, etc.) in the information added to Word, remove it.

 

Below are screenshots that show the process of copying the omacetaxine monograph title —

A screenshot shows the process of selecting and copying the monograph title.

 — and pasting it into a Word document.

A screenshot of the monograph title pasted into a Word document.

Chemical/Scientific Name

  • If the chemical/scientific name is simple (e.g. if it doesn’t contain a lot of punctuation marks, parentheses, brackets, etc), copy it and paste it into your Word document.

 

The screenshot below show omacetaxine’s chemical name.

A screenshot of the chemical name entry for omacetaxine in Martindale

Omacetaxine’s chemical name is too complicated for a search strategy, but the chemical name of your drug may be simpler.  

CAS Registry Number

  • Copy the number that follows the “CAS:” and paste the number into your Word document.

The hyphens/dashes are always used in CAS registry numbers.  You do not need to worry about alternate forms of CAS numbers.

The screenshots below show the location of the “CAS” number in the omacetaxine monograph — 
A screenshot of the "CAS Registry" entry in the Martindale monograph for omacetaxine.
— and pasting the number into the Word document.
A screenshot of the Word document after addition of the CAS registry number

Notes

  • Many, but not all, Martindale monographs  include a “Note” or “Notes” entry, and, on occasion, this entry includes alternate drugs names.  Copy any such names for asciminib, if any, and paste them into your Word document.

 

The screenshots below show a “Note” containing a name for omacetaxine —

A screenshot of the "Note" link in the Martindale monograph for omacetaxine

— and pasting this name into the Word document.

A screenshot of the Word document after addition of the name for omacetaxine shown in Martindale's "Note" field.

Synonyms

  • Copy the synonyms for asciminib that are written with the English alphabet.

 

The screenshot below shows the “Synonyms” line in the omacetaxine document.  The red boxed terms include a standard abbreviation and an alternate name for omacetaxine.  The two blue-boxed terms are investigational names.

A screenshot of the "Synonyms" line in Martindale's omacetaxine monograph with the two investigational names boxed in blue and two alternate names boxed in red.

In the screenshot below, the synonyms have been pasted into the Word document. 

A screenshot of the Word document showing addition of the synonyms.

“United States Adopted” and “British Approved” Names

  • Check the “United States Adopted” and “British Approved” names.

If these are listed, do they differ (even by a single character) from the names already in your document?

  • If you find a new term, paste it into your Word document.

International Nonproprietary Names

  • Check the International Nonproprietary Names to see if terms not already included in your Word document are present.  This list sometimes includes foreign generic names that are not listed in the synonyms list.
  • If additional terms are present, copy these (or the whole list)
  • Paste into your Word document. You may wish to use “Paste special” so that you can paste unformatted/plain text into your Word document.
  • Remove any terms in non-English alphabets (e.g. arabic script, chinese kongi) from your list.

The screenshot below shows copying of the international nonproprietary (foreign generic) names for omacetaxine.  Note the avoidance of names in foreign scripts.  The [rINN…] tags are not needed, but its easier to take them out of the word document than it is to copy each individual line separately.

A screenshot of omacetaxine's "international nonproprietary names" as listed in Martindale's

Preparations: Single Preparation

  • Look at the navigation panel on the left-hand side of the page.
  • Click on the “Preparations: Single-Ingredient” link.

 

A screenshot of the navigation panel of the Martindale monograph for omacetaxine

  • Copy the list of single-ingredient preparation names.  This list includes U.S. and foreign brand/trade/proprietary names.
  • Paste these into your Word document.  Again, you may wish to use “paste special” to paste unformatted plain text into your document.
The screenshots below show copying of the proprietary names for omacetaxine —
A screenshot of the "Preparations: Single-ingredient" list in the Martindale monograph for omacetaxine.

— and pasting into the Word document.

A screenshot of the Word document after addition of the single ingredient proprietary names for omacetaxine

Is There Another Martindale’s Monograph for Your Drug

Some drugs have only one form represented by a monographsin Martindale’s.

Others have more than one Martindale’s monograph.  The additional monographs usually contain one or two new names for the drug.

  • Return to the “UpToDate LexiDrug” search results for asciminib to see if there is more than one Martindale monograph.

The screenshots shows the position of the  “Back to Search” link above the omacetaxine monograph title …

A screenshot of the "Back to Search" link.

…. and the area under the “Martindale: The Complete Drug Reference” heading that must be checked for links to second or third monographs.  There is only one “Martindale” monograph for omacetaxine.

Area that should be checked for a second monograph link.

  • If there are second or third monographs for your drug (nilotinib), repeat the tutorial steps for these monographs.  You do not have to add names to your Word document if they duplicate names that are already present, but it may be easier to add the names to the document and remove the duplicates later.

You’ve Finished Step 1

You now have completed the first step in creating a drug keyword search, gathering the alternate terms for the drug.

License

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Using Martindale's to Create a Drug Keyword Search Copyright © 2020 by Cynthia M. Schmidt is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License, except where otherwise noted.

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