For the purposes of this tutorial, pretend that you are a fourth year pharmacy student completing a critical care rotation.

Your clinical team is caring for Mrs. Jill Dilworth, a 60 year-old female.  Mrs. Dilworth has just been admitted with peritonitis (inflammation of the lining of the abdominal cavity) and septic shock (very low blood pressure and high pulse related to severe infection).

The third-year medical resident wants to treat Mrs. Dilworth

a.  with two antibiotics–

clindamycin phosphate

–and–

aztreonam

b.  as an admixture (i.e. mixed in one IV bag)

c.  diluted in either —

dextran 40/10% normal saline solution

–OR in–

normal Saline.

Will this admixture be compatible?

Which resource will you use to address this question?