2. Detailed Guidelines for the Monograph Assignment

Drug Monograph Assignment (MA) Preparation Guidelines

Each student is required to write a ONE page (excluding reference list) monograph on an FDA-approved drug.  Follow the instructions in the Canvas-based, MA1 assignment to claim a drug topic. Drug selections are on a first come, first served basis.

The written monograph is worth 50 points, and will be assessed for scientific accuracy, completeness, English grammar, punctuation, organization, and citation and reference format. The evaluation rubric for the oral monograph presentation is provided. It is critical that the written and oral monograph succinctly highlight the important properties of the drug.  Each written monograph must be typed (using a font size of 11 or higher) and must include the drug’s name (generic and at least one U.S. trade name), your name, and the drug’s chemical structure at the top of the monograph (see example in the next chapter).  For large drugs (like monoclonal antibodies or insulin), an alternate type of structural representation is appropriate.

Monograph subheadings.

1. Drug name (generic and trade names)
2. Chemical structure
3. Physicochemical properties
4. Biopharmaceutical properties
5. Pharmacokinetic properties
6. Pharmacological properties
7. Other drugs belonging to this chemical and pharmacological class
8. Therapeutic use(s)
9. Important drug-drug interactions
10. Adverse effects (main ones only)
11.  Precautions and/or contraindications
12.  Doses
13.  Dosage forms and routes of administration.
14.  Patient counseling

References

• AMA 11th edition-style in-text citations must be used. The reference list must also be in AMA 11th edition format
• The reference list is not part of the one-page length limit.
• Each monograph must cite 1 or more of each of the following reference types:

1. 1. An online drug monograph from either Clinical Pharmacology, LexiDrugs, AHFS Drug information via LexiComp, or Martindale’s via Lexicomp.
   2. A package insert (either online or in print)
   3. A journal article (either online or in print)

• Additional references may be included.

The written monograph must be submitted through Canvas by midnight Friday, October 27th . The written monograph is worth 50 points (45 for content, 5 for citation and reference style).  Monographs submitted after the 28th will not be accepted.  A document containing all the written monographs will be created and distributed to the class.

A list of 5 multiple-choice questions concerning your drug must be submitted separately, through Canvas by midnight Friday, October 27th.

Student oral presentations will begin on Monday, Oct 30 The oral presentation will contribute 50 points to the final grade.  Each student must prepare a 10-12-minute presentation (with PowerPoint) stressing their drug’s main features.  Three minutes will be available after each presentation for questions from the audience.   Approximately 10 students will present each week. Quizzes concerning the preceding week’s presentations will begin on Nov. 7th.

Purpose of this activity:

1. To serve as an introduction to, and critical evaluation of, drug information resources.
2. To apply understanding of pharmaceutical terminology.
3. To introduce students to the most common prescription and OTC drugs.
4. To gain an appreciation of important drug properties.
5. To gain experience in scientific writing.
6. To use critical thinking to produce a precise and concise monograph.
7. To gain experience in presenting scientific information.
8. To gain experience using major drug information resources.