*3b. Correcting the Drug Keyword Search – FSA1
Objectives:
- Students will recognize problems in errant drug keyword searches.
- Students will correct, if necessary, any errors in their own nilotinib search strategies.
required video
Those who received a “great job” comment on their FSA1 assignment can skip the video and proceed to the material and exercises below. All others are required to watch the video.
nilotinib keyword search video. 
Please note that the second and third “English” closed captioning options work.
Objective 1. Students will recognize problems in errant drug keyword searches.
Review the tips for troubleshooting a drug keyword search. Apply the tips as you work on the “What’s wrong with the following searches” exercises. Then apply the tips as you review and correct (if necessary) your drug keyword search.
Tips for troubleshooting drug keyword searches
Are all the needed names present?
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- Is the English generic name present?
- Are the foreign generic names present?
Ex: If nilotinib (nilotinib*) is not truncated, three, foreign generic names must be present in a niltoinib search. If nilotinib* is present, one foreign generic name must be present in the search. This foreign generic name is listed in Martindale’s as an alternatively-spelled synonym.
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- Is a single form of each of the CAS registry numbers present? Hyphens are always present in a CAS number.
There are two CAS registry numbers for nilotinib. One for nilotinib and one for nilotinib hydrochloride.
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- Are two forms of each investigational name represented in the search. A hyphenated form and a version without the hyphen (and without any spaces) should be present.
Ex. Nilotinib has a single investigational name listed in Martindale’s. Two versions of this single name must be present in an exhaustive, “nilotinib” search.
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- Are all brand names present?
Ex. Nilotinib is marketed in many countries, but as of 08/2023, a single brand name was being used for this drug.
- Are any multi-word names (any names that contain spaces) enclosed in quotes?
- Is each name separated from the adjacent name by an OR
- Are the ORs separated from each adjacent name by a space?
- Is the entire list of ORed names enclosed in parentheses?
- Were any “quoted phrases not found” by PubMed? If so, have the quotes been removed and any spaces replaced by hyphens?
What’s wrong with the following searches?
As shown in the video, the nilotinib search retrieved 2,714 results on 3/23/2023.
( The search strategy below retrieved 130 results on 3/23/2023. All are relevant.)
(“641571-10-0” OR “923288-90-8” OR “AMN-107” OR “AMN107” OR “Nilotynib” OR “Nilotinibu*” OR “Nilotinibi” OR “Tasigna”)
The search below retrieved 52 results on 3/23/2023.
(nilotinib*OR “641571-10-0” OR “923288-90-8” OR “AMN-107” OR “AMN107” OR “Nilotynib” OR “Nilotinibum” OR “Nilotinibi” OR “Tasigna”)
( The search strategy below retrieved 0 results on 3/23/2023.)
(nilotinib* OR “641571-10-0 OR “923288-90-8” OR “AMN-107” OR “AMN107” OR “Nilotynib” OR “Nilotinibum” OR “Nilotinibi” OR “Tasigna”)
(The search below retrieved 1 result on 5/25/2022.)
(nilotinib*;641571-10-0;923288-90-8;AMN-107; AMN107;Nilotynib;Nilotinibum;Nilotinibi;Tasigna)
6.
(The search below retrieved 4,620 results on 3/23/2023. Most have nothing to do with nilotinib.)
(“nilotinib*” OR “641571-10-0” OR “923288-90-8” OR AMN* OR “Nilotynib” OR “Nilotinibum” OR “Nilotinibi” OR “Tasigna”)
Assignment and Objective 2. Students will correct, if necessary, any errors in their own nilotinib search strategies
Work with one or two other members of your class. Check your own nilotinib search and another classmate’s nilotinib search for errors. List and correct any errors that either you or your classmate found in your assignment.
If you don’t know of another classmate who’s ready to work on checking assignments, you may, instead of working with a classmate, list and correct any errors in the following “sample search” in addition to listing problems with and correcting your own search.
nilotinibiOR nilotinibumOR AMN-107OR AMN107OR NilotinibOR TasignaOR “641571-10-0″OR “923288-90-8”
Submit your work through Canvas as your “FSA1 corrected” assignment. Be sure to include the following in your Word document:
- Your name
- The name of the classmate who co-checked your assignment and whose assignment you checked (or the corrected sample search with list of errors found in the original sample search).
- Your original nilotinib search strategy, list of errors found in your original nilotinib search strategy, and your corrected nilotinib search strategy.
Questions, Problems, Text Errors?
Before you leave, …
- Do you have any questions or do you feel that clarification of some aspect of the materials would be helpful?
- Have you noticed any errors or problems with course materials that you’d like to report?
- Do you have any other comments?
If so, you can submit questions, comments, corrections, and concerns anonymously — or with your e-mail (your choice) — through this online form . Alternatively, you’re always welcome to contact Cindy Schmidt directly 402-650-5056, cmschmidt@unmc.edu, or by making an appointment to meet with Cindy via Zoom.
Answers to questions or requests for clarification that are submitted anonymously will be answered in Canvas on the “Discussions” page for this course.
